Current Treatable Diseases

Today, cord blood stem cells transplants have taken place around the world to treat more than 70 diseases. The following is a list of diseases that have been treated with cord blood and other sources of stem cell, like bone marrow.

Acute Leukemias

Acute Biphenotypic Leukemia
Acute Lymphocytic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Undifferentiated Leukemia

Chronic Leukemias

Chronic Lymphocytic Leukemia (CLL)
Chronic Myelogenous Leukemia (CML)
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)

Myelodysplastic Syndromes

Amyloidosis
Chronic Myelomonocytic Leukemia (CMML)
Refractory Anemia (RA)
Refractory Anemia with Excess Blasts (RAEB)
Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
Refractory Anemia with Ringed Sideroblasts (RARS)

Stem Cell Disorders

Aplastic Anemia (Severe)
Congenital Cytopenia
Dyskeratosis Congenita
Fanconi Anemia
Paroxysmal Nocturnal Hemoglobinuria (PNH)

Myeloproliferative Disorders

Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (Myelofibrosis)
Essential Thrombocythemia
Polycythemia Vera

Lymphoproliferative Disorders

Hodgkin's Disease
Non-Hodgkin's Lymphoma
Prolymphocytic Leukemia

Phagocyte Disorders

Chediak-Higashi Syndrome
Chronic Granulomatous Disease
Neutrophil Actin Deficiency
Reticular Dysgenesis

Liposomal Storage Diseases

Adrenoleukodystrophy
Gaucher's Disease
Hunter's Syndrome (MPS-II)
Hurler's Syndrome (MPS-IH)
Krabbe Disease
Maroteaux-Lamy Syndrome (MPS-VI)
Metachromatic Leukodystrophy
Morquio Syndrome (MPS-IV)
Mucolipidosis II (I-cell Disease)
Mucopolysaccharidoses (MPS)
Niemann-Pick Disease
Sanfilippo Syndrome (MPS-III)
Scheie Syndrome (MPS-IS)
Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)
Wolman Disease

Histiocytic Disorders

Familial Erythrophagocytic Lymphohistiocytosis
Hemophagocytosis
Histiocytosis-X
Langerhans' Cell Histiocytosis

Inherited Erythrocyte Abnormalities

Beta Thalassemia Major
Blackfan-Diamond Anemia
Pure Red Cell Aplasia
Sickle Cell Disease

Congenital (Inherited) Immune System Disorders

Absence of T & B Cells SCID
Absence of T Cells, Normal B Cell SCID
Ataxia-Telangiectasia
Bare Lymphocyte Syndrome
Common Variable Immunodeficiency
DiGeorge Syndrome
Kostmann Syndrome
Leukocyte Adhesion Deficiency
Omenn's Syndrome
Severe Combined Immunodeficiency (SCID)
SCID with Adenosine Deaminase Deficiency
Wiskott-Aldrich Syndrome
X-Linked Lymphoproliferative Disorder

Other Inherited Disorders

Cartilage-Hair Hypoplasia
Ceroid Lipofuscinosis
Congenital Erythropoietic Porphyria
Glanzmann Thrombasthenia
Lesch-Nyhan Syndrome
Osteopetrosis
Tay Sachs Disease

Inherited Platelet Abnormalities

Amegakaryocytosis / Congenital Thrombocytopenia

Plasma Cell Disorders

Multiple Myeloma
Plasma Cell Leukemia
Waldenstrom's Macroglobulinemia

Other Malignancies

Brain Tumors
Breast Cancer
Ewing Sarcoma
Neuroblastoma
Ovarian Cancer
Renal Cell Carcinoma
Small-Cell Lung Cancer
Testicular Cancer

Autoimmune Diseases

Evan Syndrome
Multiple Sclerosis (Experimental)
Rheumatoid Arthritis (Experimental)
Systemic Lupus Erythematosus (Experimental)

Banking cord blood does not guarantee that the cells will provide a cure or be applicable for every situation. The treating physician will determine the ultimate use. The newborn may be able to use his or her cord blood for some of the conditions on this list, but not all. In some cases, a matched sibling’s stem cells would be the first choice. There is no guarantee that the umbilical cord blood will be a match for a family member or will provide a cure. Autologous cord blood stem cells will not guarantee suitable treatment for all inherited genetic diseases. As with any transplant therapy, therapeutic success depends upon many factors beyond the stem cells themselves including patient condition, type of disease, recipient-donor relationship and matching, and other factors. The use of cord blood stem cells for emerging treatments is experimental. Please consult your physician.